Winning projects

1. Development and testing of new grafting wax against chestnut blight

2. Determining coronary-circulation based on intracoronal pressure and three-dimensional coronary reconstruction

3. Development and production of a new gastroretentive dosage form

4. Production and in vivo testing of manganese based MRI contrast agents

5. New diagnostic method for breast cancer based on bacterial dysbiosis

6. Development of digestion friendly liquid product to supplement energy and rehydration during long distance physical activity

7. Trichoderma based bipesticide

 

Development and testing of new grafting wax against chestnut blight

Lead researcher: Dr. László Radócz, head of department, Institute of Plant Protection
 

Bioagent-based grafting wax against chestnut blight (Cryphonectria parasitica). The product is also a pesticide that contains the hypovirulent strains of the pathogenic fungus. The hypovirulent strains infect the virulent strains weakening the pathogen, then the cankers are healed by callus production. As a result of this development we expect the product to be used for preventive purposes as well as for treatment, and it could be used without any regulations to produce grafts for conventional, eco-friendly manufacturers.

 

Determining coronary-circulation based on intracoronal pressure and three-dimensional coronary reconstruction

Lead researcher: Dr. Zsolt Kőszegi, associate professor, Department of Cardiology

A method that helps the medical decision making process during treatments of patients with Coronary Artery Disease. The method determines the Coronary Flow Reserve (CFR) with the help of Coronary artery reconstruction and the intracoronal pressure data derived from FFR measures. This evaluation method enables medical professionals to be able to better determine the extent of coronary stenosis and provide treatment that is more effective. The developed module can be used by installing it into X-ray machines.

 

Development and production of a new gastroretentive dosage form

Lead researcher: Dr. Ferenc Fenyvesi, senior lecturer, Department of Pharmaceutical Technology

The project is targeting the development and production of gastroretentive hard gelatin capsule. The product is expected to enable prolonged drug release in the stomach and to improve the bioavailability of drugs. The absorption time in the stomach could be extended up to 8 hours improving the efficiency of drugs. The development is expected to be especially beneficial in the following two cases: local treatment of the stomach and helping the absorption of active substances that act on the circulatory system.

 

Production and in vivo testing of manganese based MRI contrast agents

Lead researcher: Dr. Gyula Tircsó, head of department, Department of Physical Chemistry

Manganese based MRI contrast agents can be serious competitors to gadolinium based contrast agents used in Magnetic resonance imaging. Based on in vitro studies, manganese based contrast agents satisfy the requirements regarding contrast agents and are potentially less toxic and have better biocompatibility indicators than the gadolinium based agents that are currently on the market.

 

New diagnostic method for breast cancer based on bacterial dysbiosis

Lead researcher: Dr. Péter Bay, professor, Department of Medical Chemistry

The project targets the development and commercialization of a new diagnostic system for early stage breast cancer. Even with the help of modern diagnostics, the early recognition of tumors is not always possible. The technology could make it possible to  recognize tumors with simple, non-invasive stool tests. Similarly to other tumor markers, the technology can potentially be also used to monitor the efficacy of tumor therapy or early remission. With further research it is possible to use the method to diagnose cancerous diseases.

 

Development of digestion friendly liquid product to supplement energy and rehydration during long distance physical activity

Lead researcher: Nóra Őri, associate research fellow, Agricultural Laboratory Center

A supplementary drink primarily developed for athletes. The product moderates the physiological difficulties and problems caused or not completely solved by similar products on the market. The drink provides efficient energy boost with the help of plant derived polysaccharides and does not contain simple sugars providing longer absorption time. These natural ingredients are digestion-friendly and the flavor enhancing ingredients also have nutritional value.

 

Trichoderma based bipesticide

Lead researcher: Dr. Erzsébet Karaffa, associate professor, Institute of Food Science

Trichoderma based biopesticide that provides an opportunity to improve the condition of plants, primarily grapevines. The method is similar to probiotics already used in human and veterinary medicine, it improves the resistance against different diseases caused by biotic and abiotic stress. The identified strains can survive in grapevines better than other products on the market. The developed product can potentially enhance the immunity of the plant and due to its micoparasitic ability to destroy harmful fungi it can control the growth of plant pathogen fungi. The technology can be used to prevent and/or treat Grapevine Trunk Disease as well as to stimulate plant growth.

Updated: 2019.07.29.


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